Tana, a female French bulldog, went to a veterinary center for his first vaccination. The size larger than normal "in her clitoris alerted the specialists who carried out the appropriate tests. analysis first identified in the world of reproductive genetic alteration in this race: the dog had cryptorchid testes (not the scrotum). His case appears in a study published in the journal "Reproduction in Domestic Animals'.
The genetic alteration of the reproductive and sexual reversion "is described in many species such as goats, swine, equine, and even human," said Mark Fields SINC, author of the study, researcher at the CEU-Cardenal Herrera University and director of assisted reproduction center for small animals Reprovalcan.
The dog Tana, three months old at their first visit, had a diagnosis consistent with a genetic disorder of the reproductive tract, had a large clitoris. "It was a female XX chromosomes but with male gonads (testicles cryptorchid) due to the presence of other genes that determine the testicular formation in the absence of the genes on the Y chromosome, "explains Campos.
The alteration, which has also been reported in 18 other races dogs in the world, is "uncommon but can occur." sexual reversal causes sterility and, ultimately, may predispose to diseases such as infections or tumors of the gonads, "not be a normal genital," says veterinarian.
The study showed that the urethra into the bladder directly ended, and the clitoris, 0.8 inches long, contained penis bone, which predisposed to urinary tract infections and infertility was studying for the dog. Hermaphroditism
dog with a happy ending
The dog, which is the first documented case of French bulldog with this change in the world, had a mild degree of masculinization, and that despite the size of the clitoris, vulva was normal. To avoid any medical complications in Tana, the best option was surgical sterilization, which was removed completely genital, which was later sent to the histopathology laboratory. "Today, the dog is in perfect condition," says Campos. veterinarians suggest that parents of the puppies are removed from hermaphroditic breeding program because "it is expected that at least half of the litter is a carrier." Siblings of affected dogs should not reproduce until they are able to identify the mutant genes, which would eliminate the carriers. However, still no data on the affected dogs of this particular race, but would determine the pattern of inheritance. According to genetic models of other races, this is an autosomal recessive disorder (the animal only needs to receive the abnormal gene from one parent to inherit the reversal).
http://www.elmundo.es/elmundo/2011/03/24/ciencia/1300963213.html
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